psilocybin
A recent pilot study published in the Journal of Psychedelic Studies has found preliminary evidence that psilocybin, when administered in a group retreat setting, can enhance psychological flexibility. The findings suggest that changes in psychological flexibility may play a crucial role in the therapeutic benefits of psilocybin experiences. Psilocybin is a naturally occurring psychedelic compound found in over 200 species of mushrooms, known colloquially as “magic mushrooms.” When ingested, psilocybin is converted into psilocin in the body, which then influences serotonin receptors in the bra...
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Recent scientific advancements have shed light on the potential synergistic effects of meditation and psychedelic substances. A study published in Scientific Reports reveals how psilocybin, a psychedelic compound, when combined with open monitoring meditation may enhance the depth of insightfulness in experienced meditators. This enhancement appears to be mediated by changes in the brain’s organizational patterns. Open monitoring meditation is a type of meditation that emphasizes the broad, non-reactive awareness of the content of experience from moment to moment. Unlike focused attention medi...
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In recent years, interest in psychedelic-assisted therapy has grown due to its potential to treat various psychological disorders such as depression, anxiety, and post-traumatic stress disorder. However, a new study published in the Journal of Psychedelic Studies raises important concerns. It suggests that while there may be benefits, there are also significant risks. The study focuses on the negative effects reported by therapists who facilitate such treatments, highlighting that the impacts of psilocybin are not universally beneficial and can vary widely from one individual to another. Psilo...
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Scientists have recently discovered that psilocybin, the active ingredient in “magic mushrooms,” can significantly reduce chronic pain in rats. Notably, this pain relief was related to pain from touch, but not pain from heat. The study was published in Current Biology01374-X). Psychedelic drugs have recently gained attention for their potential to treat various psychiatric disorders. Psilocybin, in particular, has been the subject of research for its therapeutic effects on treatment-resistant depression as well as alcohol and tobacco abuse. Led by Nicholas Kolbman, researchers from the Univers...
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Scientists have started to investigate whether a compound found in magic mushrooms, psilocybin, could play a role in combating the effects of diabetes. According to their preliminary research, published in the journal Genes, psilocybin might help prevent the loss of critical insulin-producing cells in the pancreas. Psilocybin is a naturally occurring psychedelic compound found in certain species of mushrooms. In recent years, its therapeutic potential has begun to be recognized, particularly for mental health conditions. The rationale for this study, however, stems from psilocybin’s interactio...
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A recent study examined the role of patient expectations in influencing the outcomes of treatments with psilocybin, a psychedelic substance, compared to escitalopram, a widely prescribed antidepressant. Contrary to what some might expect, the study did not find a significant link between patients’ expectations and their actual responses to psilocybin therapy. However, the study also indicates that individuals who are more suggestible might experience a greater benefit from this treatment. The findings have been published in the journal Psychological Medicine. Depression’s staggering global imp...
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In recent years, the scientific community has turned its attention back to the potential of psychedelics as therapeutic agents, with psilocybin, a naturally occurring substance found in certain mushrooms, at the forefront of this research. A new study published in the journal Molecular Psychiatry suggests possible benefits of using psilocybin-containing mushroom extract over its chemically synthesized counterpart for the treatment of psychiatric disorders such as depression, PTSD, obsessive-compulsive disorders, and anxiety. “My colleagues and I are very interested in the potential of psychede...
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A recent study published in Scientific Reports reveals new insights into how psilocybin-assisted therapy modifies brain function in people with alcohol use disorder (AUD). These changes suggest a potential mechanism behind the therapy’s success and could point toward new avenues for treatment. Psilocybin is the psychoactive compound found in certain species of mushrooms, often referred to as “magic mushrooms,” known for its ability to produce profound changes in consciousness, perception, and mood. Psilocybin-assisted therapy combines the administration of psilocybin with psychological support...
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Recent research conducted by teams from the Center for Psychedelic and Consciousness Research at Johns Hopkins School of Medicine and the Centre for Psychedelic Research at Imperial College London has taken a significant step forward in understanding the therapeutic mechanisms behind psilocybin therapy for treating major depressive disorder (MDD). Their study, published in the International Journal of Mental Health and Addiction, reveals that specific psychological experiences during psilocybin therapy, particularly mystical experiences and ego dissolution, play a critical role in the therapy’...
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New research published in Molecular Psychiatry provides insight into how psilocybin, a compound found in psychedelic “magic” mushrooms, influences the brain and behavior. By observing the effects of psilocybin on larval zebrafish, scientists uncovered that it not only stimulates exploratory behavior but also buffers against stress-induced changes in activity patterns. This investigation sheds light on the complex interplay between psychedelic compounds and the serotonergic system — the part of the brain that helps regulate mood, anxiety, and happiness. What is Psilocybin, and Why Focus on It?P...
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