treatment
Washington (AFP) - A new treatment shows promise against the deadly neurodegenerative disease ALS, a study based on mice showed Tuesday. Amyotrophic lateral sclerosis, sometimes called Lou Gehrig's disease after the famous baseball player, devastates nerve cells in the brain and spinal cord. It affects about 30,000 Americans at any given time, causing progressive loss of motor and cognitive function. Most patients die within five years of their diagnosis. In the new research, published in the journal PLOS Biology, a team led by Jeffrey Agar of Northeastern University investigated a way to ta...
AFP
Geneva (AFP) - The World Health Organization said Friday it "strongly recommended" Pfizer's Covid-19 antiviral pill Paxlovid for patients with milder forms of the disease who were still at a high risk of hospitalisation. However the UN agency warned it was "extremely concerned" that the inequality in access seen with Covid vaccines would again leave low- and middle-income countries "pushed to the end of the queue". US pharma giant Pfizer's combination of nirmatrelvir and ritonavir was the "superior choice" of treatment for unvaccinated, elderly or immunocompromised people with Covid, the WHO's...
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Washington (AFP) - US biotech firm Regeneron said Tuesday that its synthetic antibody treatment for Covid-19 may be less effective against the new variant, and it plans to conduct tests to determine by how much. "Prior in vitro analyses and structural modeling regarding the individual mutations present in the Omicron variant indicate that there may be reduced neutralization activity of both vaccine-induced and monoclonal antibody-conveyed immunity, including the current REGEN-COV antibodies," the company said in a statement. "Further analyses are ongoing to confirm and quantify this potential ...
AFP
Washington (AFP) - US scientists have developed a new form of drug that promotes the regeneration of cells and reversed paralysis in mice with spinal injuries, allowing them to walk again within four weeks of treatment. The research was published in the journal Science on Thursday, and the team of Northwestern University scientists behind it hope to approach the Food and Drug Administration as early as next year to propose human trials. "The aim of our research was to develop a translatable therapy that could be brought to the clinic to prevent individuals from becoming paralyzed after major t...
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Washington (AFP) - A synthetic antibody treatment developed by Regeneron reduced the risk of developing symptomatic Covid by more than 80 percent up to eight months after receiving the treatment, the US biotech firm said Monday. The results are "particularly important to those who do not respond to COVID-19 vaccines including people who are immunocompromised," said Myron Cohen, a University of North Carolina at Chapel Hill scientist who is leading a government-sponsored study into the treatment. The study included 842 people who received a placebo and 841 who received the treatment, known as R...
AFP
Washington (AFP) - The United States on Wednesday announced an agreement with Merck to buy 1.7 million courses of an experimental antiviral pill against Covid-19. The $1.2 billion dollar deal is for a drug called molnupiravir, which is currently being tested in a global Phase 3 clinical trial of 1,850 people, with results expected by fall. "This agreement is part of the Biden Administration's whole-of-government approach to develop new COVID-19 treatments and to respond to the health needs of the public," the Department of Health and Human Services said. The US will only complete the deal if m...
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Washington (AFP) - A Covid-19 antibody therapy used to treat President Donald Trump was approved by the US drug regulator on Saturday for people who aren't yet hospitalized by the disease but are at high risk.The green light for drugmaker Regeneron came after REGEN-COV2, a combination of two lab-made antibodies, was shown to reduce Covid-19-related hospitalizations or emergency room visits in patients with underlying conditions."Authorizing these monoclonal antibody therapies may help outpatients avoid hospitalization and alleviate the burden on our health care system," said Stephen Hahn, comm...
AFP
Washington (AFP) - The US Food and Drug Administration on Monday granted emergency approval to a synthetic antibody treatment against Covid-19 developed by Eli Lilly, after the drug was shown to reduce the risk of hospitalization and emergency room visits.Bamlanivimab at a dose of 700 milligrams was authorized for the treatment of mild-to-moderate Covid-19 in adults and children aged 12 years and older who are at high risk for progressing to the severe form of the disease.It is the first major drug to be approved that was designed specifically against the new coronavirus."As illustrated by tod...
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Washington (AFP) - The US Food and Drug Administration on Thursday granted full approval to the antiviral drug remdesivir as a treatment for patients hospitalized with Covid-19, after conditional authorization was given in May.Gilead said the drug, sold under the brand name Veklury, was the only specific treatment for Covid-19 approved so far under a more rigorous process.However, other treatments have received authorization for emergency use, though that approval can be revoked once the public health emergency sparked by the coronavirus pandemic is over.Other medications, like the steroid dex...
AFP
Washington (AFP) - Two US companies have applied for emergency approval for their lab-produced antibodies against Covid-19 -- and President Donald Trump has signaled his strong backing based on the fact he was treated with one of them.Here's what we know about the treatments and why the perception of political interference at the Food and Drug Administration may have eroded public trust.What are they? - The therapies developed by Regeneron and Eli Lilly are called "monoclonal antibodies," a relatively new class of drugs that are best known for treating certain types of cancer and autoimmune di...
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